VALIUM is usually a federal managed compound (C-IV) as it consists of diazepam that can be abused or lead to dependence. Maintain VALIUM in a secure area to forestall misuse and abuse.
Second dose: When needed, could possibly be administered following at least four hr soon after Original dose; if the second dose is administered, use a new blister pack of diazepam intranasal
fentanyl iontophoretic transdermal process and diazepam both improve sedation. Prevent or Use Alternate Drug. Limit use to patients for whom different procedure options are inadequate
eslicarbazepine acetate will decrease the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
cyclophosphamide will enhance the amount or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.
mitotane decreases levels of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Mitotane is a solid inducer of cytochrome P-4503A4; keep an eye on when coadministered with CYP3A4 substrates for possible dosage adjustments.
Severe lung condition or respiration complications, such as a issue termed significant respiratory insufficiency
Abuse and misuse of benzodiazepines frequently (although not generally) involve utilization of doses larger than the most proposed dosage and commonly involve concomitant use of other medicines, alcohol, and/or illicit substances, which can be affiliated with an elevated frequency of great adverse outcomes, which includes respiratory despair, overdose, or Demise
ethinylestradiol will enhance the amount or impact of diazepam by Mechanism: reducing metabolism. Use Caution/Monitor. Ethinyl estradiol might inhibit the clearance of benzodiazepines that undertake oxidation, thereby expanding serum concentrations of concomitantly administered benzodiazepines.
oxcarbazepine will lessen the extent or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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activity to be a neuronal voltage gated calcium channel blocker in rats.34 In addition it binds to a unique benzodiazepine receptor,
Usually do not share diazepam with other people, even if they've got the identical situation as you. It may harm them.
prednisone will decrease the extent or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.